Predicting site-specific human selective pressure using evolutionary signatures
نویسندگان
چکیده
منابع مشابه
Predicting site-specific human selective pressure using evolutionary signatures
MOTIVATION The identification of non-coding functional regions of the human genome remains one of the main challenges of genomics. By observing how a given region evolved over time, one can detect signs of negative or positive selection hinting that the region may be functional. With the quickly increasing number of vertebrate genomes to compare with our own, this type of approach is set to bec...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2011
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btr241